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Chapter Subsections

Basics
How Has Wilson’s Temperature Syndrome Gone Overlooked?
Limitations of Thyroid Blood Tests
Diagnosis and Pretreatment Considerations
If Considering a Therapeutic Trial of Thyroid, Why Not Use T4?
Workup for T3 Therapy
Treatment Principles
Timing of Doses, Compliance
Monitoring, Compliance and Steadiness
Unsteadiness and the T4 Test Dose
Risks, Benefits, and Myths
T3 Therapy In Hypothyroid Patients (& euthyroid patients presenting on T4-containing medicine)
Time Zones, Pregnancy, Surgery, Drugs, & Other T3 Therapy Tidbits

In this section

Basics
Not only can the “low thyroid” symptoms of patients with normal thyroid blood tests respond beautifully to the right thyroid medicine given in the right way, but they can also remain improved even after the treatment has been discontinued.
Diagnosis and Pretreatment Considerations
Although many conditions can cause symptoms similar to those of Wilson’s Temperature Syndrome, there are several reasons that Wilson’s Temperature Syndrome should be considered frist and not last, in patients with these types of symptoms.
How Has Wilson’s Temperature Syndrome Gone Overlooked?
Not necessarily. Some faulty assumptions have played a major role in this condition being overlooked by so many for so long. This condition has not been so easily recognized in the past, because doctors didn’t have a way to get it better.
If Considering a Therapeutic Trial of Thyroid, Why Not Use T4?
In my experience, the “resetting phenomenon” doesn’t really occur with the use of T4-containing medicines (which can actually make Wilson’s Temperature Syndrome worse).
Limitations of Thyroid Blood Tests
The body temperature is a result of the thyroid stimulation of the cells. Trying to manage a patient on thyroid medicine using only thyroid blood tests as a guide is a little like trying to write your name with a floppy pencil.
Monitoring, Compliance and Steadiness
Looking out over the ocean, it’s easy to tell whether it is high tide or low tide, and weather conditions are choppy or calm. Body temperature patterns, as well as patient response, help guide T3 therapy. Thyroid blood tests do not direct therapy per se.
Risks, Benefits, and Myths
Possible aggravation of cardiovascular predispositions. The major risk is cardiovascular. I don’t advise using T3 therapy in patients with low cardiovascular reserve. The risks are more short-term than long-term.
T3 Therapy In Hypothyroid Patients (& euthyroid patients presenting on T4-containing medicine)
Hypothyroidism is low thyroid gland function. But the symptoms of low thyroid system function are more commonly caused by Wilson’s Temperature Syndrome, not hypothyroidism. People diagnosed as hypothyroid who are taking T4-containing medicine may never have been hypothyroid, or if they were, may not be now.
Time Zones, Pregnancy, Surgery, Drugs, & Other T3 Therapy Tidbits
If a drug does not interact with the T3 a patient’s own body makes, then it will not chemically interact with the T3 therapy she takes by mouth. However, T3 therapy can interact indirectly with other medicines in that all medicines can have side effects, and those side effects can be additive.
Timing of Doses, Compliance
How well on time the T3 doses are taken is very important to the overall steadiness of the T3 levels. If 100 patients were on T3 therapy and were missing their doses by 15 minutes here, and 20 minutes there, about 60% of them would be responding pretty well to the treatment.
Treatment Principles
Feeling well on T3 therapy has everything to do with the T3 stimulation being strong enough to get the temperature up to normal, and steady enough to be well tolerated. With T3, steadiness is everything. The two goals of T3 therapy are: 1. To feel well while on T3 therapy.
Unsteadiness and the T4 Test Dose
As mentioned previously, a person may get characteristic side effects if the T3 levels become unsteady. A lot of what people think are symptoms of thyroid toxicity are really due to thyroid hormone level unsteadiness.
Workup for T3 Therapy
Evaluation of the numerous possible symptoms can often be facilitated by asking patients to fill out a Symptom Checklist (internet connection must be active for this link to work).

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Sustained-release T3 for low body temperature — the WT3 protocol.

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